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Medicine name : Clolar
Generic name : Clofarabine
Manufactured By : Sanofi
Indications : Relapsed or Refractory ALL
Medicine Description : Clolar is a purine nucleoside analog used for pediatric acute lymphoblastic leukemia (ALL). It disrupts DNA synthesis, leading to cancer cell death. Given via IV, it is used in relapsed or refractory cases. Side effects include liver toxicity, low blood counts, and infections. Close monitoring of liver function and blood cell levels is essential to prevent complications.
Clolar (Clofarabine) is a prescription chemotherapy drug used to treat relapsed or refractory acute lymphoblastic leukemia (ALL) in children and young adults aged 1 to 21 who have tried at least two other treatments.
Clolar is a purine nucleoside analog. It interferes with DNA synthesis in cancer cells, stopping them from growing and multiplying, which leads to their destruction.
Clolar is approved for pediatric and young adult patients (1–21 years old) with ALL who have not responded to or have relapsed after two or more chemotherapy treatments.
Clolar is administered as an intravenous (IV) infusion in a hospital or clinic, usually once daily for 5 days in a treatment cycle.
Common side effects include fever, nausea, vomiting, diarrhea, rash, low blood counts, and increased liver enzymes.
Yes, Clolar can cause serious side effects such as liver toxicity, kidney problems, low blood pressure, infections, and bone marrow suppression. Contact your doctor if you notice symptoms like dark urine, yellowing of the skin, or swelling.
Treatment duration is determined by your doctor based on how you respond and tolerate the drug. It may continue for multiple cycles if effective.
It’s best to avoid alcohol, as it can increase the risk of liver damage and worsen side effects like dizziness or nausea.
No, Clolar may harm an unborn baby. Patients should avoid pregnancy during treatment and use effective birth control.
Yes, Clolar can interact with other drugs, especially those affecting the liver or kidneys. Always inform your doctor of any medications or supplements you are taking.
Since Clolar is given in a clinical setting, your medical team will manage any missed doses or treatment adjustments.
Clolar is administered via IV infusion, so food intake does not affect its use.
Monitor for signs of infection, avoid crowded or sick places, stay hydrated, and attend all scheduled blood tests and medical appointments.
Clolar is stored and handled by healthcare professionals in a hospital or clinic setting.
Clolar is available through hospitals or oncology centers and is administered by trained healthcare providers. Talk to your doctor for access and scheduling. Pharma Five assists in its procurement.