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Buy Lysodren (Mitotane) Medicine in India

Lysodren (Mitotane)

Medicine name : Lysodren

Generic name : Mitotane

Manufactured By : Hra Pharma

Indications : Adrenal carcinoma and inoperable adrenal cortical carcinoma

Medicine Description : Lysodren is a steroidogenesis inhibitor used for adrenocortical carcinoma (ACC). It disrupts hormone production in adrenal tumors, slowing cancer growth. Taken orally, it helps control symptoms. Side effects include nausea, fatigue, dizziness, and adrenal insufficiency. Hormone level monitoring is essential to prevent severe side effects.

Product Introduction

Lysodren (Mitotane) is an anticancer medicine used to treat adrenocortical carcinoma (ACC), a rare cancer that develops in the outer layer of the adrenal glands. It works by damaging adrenal cancer cells and reducing the production of adrenal hormones, helping to control tumor growth and hormone-related symptoms.

Lysodren (Mitotane) should be taken exactly as prescribed by your doctor, usually in divided doses throughout the day and with meals containing fat to improve absorption. Swallow the tablets whole with water and do not crush or chew them. Treatment may require careful dose adjustment based on blood levels of Mitotane and your response to treatment. Your doctor may also prescribe corticosteroid replacement because Mitotane can significantly reduce adrenal hormone production.

Common side effects of Lysodren may include loss of appetite, nausea, vomiting, diarrhea, abdominal discomfort, dizziness, weakness, fatigue, and changes in hormone levels. It may also cause serious adrenal insufficiency, nervous-system effects, or liver problems. Inform your doctor promptly if you experience severe weakness, dizziness, confusion, vomiting, diarrhea, yellowing of the skin or eyes, or other concerning symptoms. Regular blood tests and monitoring of hormone levels, liver function, and Mitotane levels may be required during treatment.

Uses Of Lysodren (Mitotane)

Treatment of Adrenocortical Carcinoma

Benefits Of Lysodren

Lysodren (Mitotane) is used to treat adrenocortical carcinoma (ACC), a rare cancer that develops in the outer layer of the adrenal glands. It works by damaging adrenal cancer cells and reducing the production of adrenal hormones. This helps control the growth and spread of adrenal cancer and may also help manage symptoms caused by excessive production of adrenal hormones.

Side Effects Of Lysodren (Mitotane)

Some side effects of Lysodren (Mitotane) may improve as your body adjusts to the medicine. Consult your doctor if any side effect persists, becomes severe, or causes concern.

Common Side Effects of Lysodren (Mitotane)

  • Loss of appetite
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort
  • Fatigue
  • Weakness
  • Dizziness
  • Headache
  • Skin rash
How To Use Lysodren

Lysodren (Mitotane) should be taken exactly as prescribed by your doctor. It is usually taken in divided doses throughout the day and should be taken with food, preferably meals containing fat, to improve absorption. Swallow the tablets whole with water and do not crush or chew them. The dose may be gradually adjusted based on Mitotane blood levels, your response to treatment, and tolerance. Your doctor may also prescribe corticosteroid replacement during treatment.

How Lysodren (Mitotane) Works

Lysodren (Mitotane) is an adrenolytic medicine that acts directly on cells of the adrenal cortex. It damages adrenal cancer cells and reduces the production of adrenal hormones such as cortisol. By affecting these cells and hormone production, Mitotane helps control the growth of adrenocortical carcinoma (ACC) and manage symptoms caused by excess adrenal hormones.

Storage Conditions
  • Store Lysodren at a controlled room temperature of approximately 25°C.
  • Temperature excursions between 15°C and 30°C are permitted.
  • Keep the bottle tightly closed and dispense the tablets in a tight container.
  • Store the medicine securely and keep it out of the reach of children.
Safety Advice

AlcoholAlcohol CONSULT YOUR DOCTOR

Consult your doctor before consuming alcohol during treatment with Lysodren (Mitotane).

PregnancyPregnancy CONSULT YOUR DOCTOR

Lysodren (Mitotane) may harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant. Use effective contraception as advised by your doctor.

BreastfeedingBreastfeeding CONSULT YOUR DOCTOR

Do not breastfeed during treatment with Lysodren (Mitotane). Consult your doctor for guidance.

DrivingDriving CONSULT YOUR DOCTOR

Lysodren may cause dizziness, drowsiness, or weakness and can affect your ability to drive. Avoid driving if these symptoms occur.

KidneyKidney CAUTION

Inform your doctor if you have kidney problems before starting treatment. Your doctor may recommend appropriate monitoring.

LiverLiver CAUTION

Tell your doctor if you have liver problems. Mitotane can affect liver function, so your doctor may monitor liver function regularly.

Quick Tips
  • Take Lysodren (Mitotane) exactly as prescribed and take it with food as advised by your doctor.
  • Attend regular blood tests to monitor Mitotane levels, hormone levels, liver function, and your overall response to treatment.
  • Take any prescribed corticosteroid replacement regularly and do not stop it suddenly without your doctor's advice.
  • Contact your doctor promptly if you develop severe weakness, dizziness, vomiting, diarrhea, confusion, or other symptoms that may indicate low adrenal hormone levels.
  • Inform your doctor about all medicines, vitamins, herbal products, and dietary supplements you are taking to help prevent possible drug interactions.
  • Read More About - Lysodren (Mitotane) from Pharma Five.
About Pharma Five

Pharma Five, may facilitate patients in importing Lysodren (Mitotane) in small quantities for personal medical use. To complete the import process, the applicant is required to submit an application in Form 12A along with a prescription issued by a Registered Medical Practitioner (RMP).

Pharma Five supports patients requiring Lysodren (Mitotane) by providing professional assistance and facilitation for accessing specialized pharmaceutical products through the appropriate import process. Pharma Five provides extensive pharmaceutical service coverage across India, serving patients and healthcare requirements in prominent cities such as Mumbai, Delhi, Kolkata, Bhubaneswar, Bangalore, Hyderabad, Chennai, Ahmedbad, Pune, Surat, Visakhapatnam, Jaipur, Lucknow, Nagpur, Indore, Patna, Agartala, Guwahati, Imphal, Kohima, Namchi, Noida, Ghaziabad, Ludhiana, Agra, Varanasi, Srinagar, Amritsar, Jodhpur, Chandigarh, Gurgaon, Gorakhpur, Dehradun, Jammu, Hyderabad, Thiruvananthapuram, Kochi, Coimbatore, Puducherry, Mysuru, Salem, Vellore, Tiruppur, Guntur, Goa, Kolhapur, Mumbai, Nashik, and various other regions in India.

References
  1. https://go.drugbank.com/drugs/DB00648
  2. https://www.ema.europa.eu/en/medicines/human/EPAR/lysodren
  3. https://www.cancerresearchuk.org/about-cancer/treatment/drugs/mitotane-lysodren
Faq

General Question

Lysodren (Mitotane) is a prescription drug used to treat adrenal cortical carcinoma (ACC), a rare type of cancer affecting the adrenal glands.

Lysodren works by inhibiting the function of the adrenal cortex, reducing hormone production and slowing the growth of cancer cells.

Doctors prescribe Lysodren for adults with adrenal cortical carcinoma, especially when surgery is not an option or the cancer has spread.

Lysodren is taken orally in tablet form, usually two to four times daily, with food or milk to reduce stomach discomfort.

Common side effects of Lysodren include nausea, vomiting, dizziness, diarrhea, fatigue, and loss of appetite.

Yes, Lysodren may cause serious side effects such as adrenal insufficiency, neurological issues, and liver problems. Seek medical attention if severe symptoms occur.

Lysodren is typically taken as long as it remains effective and well-tolerated, or until the doctor advises stopping treatment.

It is best to avoid alcohol while taking Lysodren, as it may increase side effects such as dizziness and liver toxicity.

No, Lysodren may harm an unborn baby. Women should use effective contraception while taking this medication.

Yes, Lysodren may interact with anticoagulants, corticosteroids, and certain seizure medications. Inform your doctor about all medicines you take.

If you miss a dose of Lysodren, take it as soon as you remember. Skip the missed dose if its almost time for the next one. Do not take two doses together.

Yes, Lysodren can be taken with food or milk to help reduce stomach discomfort.

Avoid grapefruit, monitor adrenal function regularly, and inform your doctor if you experience severe fatigue, dizziness, or confusion.

Store Lysodren at room temperature, away from moisture and heat, and keep it out of reach of children.

Lysodren is available by prescription at pharmacies or through specialty drug providers. Consult your doctor for the best source. Pharma Five assists in its procurement.

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