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Buy Istodax (Romidepsin) Medicine in India

Istodax (Romidepsin)

Medicine name : Istodax

Generic name : Romidepsin

Manufactured By : Celgene

Indications : Cutaneous T-Cell Lymphoma (CTCL)

Medicine Description : Istodax is an HDAC inhibitor for relapsed/refractory peripheral T-cell lymphoma (PTCL). It alters gene expression, leading to cancer cell death. Given via IV infusion, it extends survival in aggressive lymphomas. Side effects include low blood counts, infections, nausea, and heart rhythm disturbances. ECG and blood count monitoring are required to manage risks.

Product Introduction

Istodax (Romidepsin) is an anticancer medicine used to treat certain types of T-cell lymphoma, including cutaneous T-cell lymphoma (CTCL) and peripheral T-cell lymphoma (PTCL), in patients whose disease has returned or has not responded adequately to previous treatments. It belongs to a group of medicines called histone deacetylase (HDAC) inhibitors and works by affecting proteins involved in cancer cell growth and survival, helping to slow or stop the growth of abnormal T-cells.

Istodax (Romidepsin) is administered by a healthcare professional through an intravenous infusion. The dose and treatment schedule are determined by your doctor based on your condition and response to treatment. Regular blood tests and medical monitoring may be required to check blood cell counts, liver function, electrolyte levels, and heart rhythm during treatment.

Common side effects of Istodax may include nausea, vomiting, fatigue, weakness, decreased appetite, fever, diarrhea, headache, and low blood cell counts. Serious side effects such as infections, bleeding, liver problems, and changes in heart rhythm may also occur. Inform your doctor promptly if you develop fever, unusual bleeding, severe weakness, fainting, irregular heartbeat, or other concerning symptoms. Before starting treatment, tell your doctor about all medical conditions and medicines, vitamins, herbal products, or supplements you are taking.

Uses Of Istodax (Romidepsin)

Treatment of T-Cell Lymphoma

Benefits Of Istodax

Istodax (Romidepsin) is used to treat certain types of T-cell lymphoma, including cutaneous T-cell lymphoma (CTCL) and peripheral T-cell lymphoma (PTCL), particularly when the disease has returned or has not responded adequately to previous treatments. It works by inhibiting histone deacetylase (HDAC) enzymes, which can interfere with the growth and survival of abnormal T-cells. This helps reduce cancer cell growth and may slow the progression of the disease.

Side Effects Of Istodax (Romidepsin)

Some side effects of Istodax (Romidepsin) may improve as your body adjusts to the medicine. Consult your doctor if any side effect persists, becomes severe, or causes concern.

Common Side Effects of Istodax (Romidepsin)

  • Nausea
  • Vomiting
  • Fatigue
  • Weakness
  • Decreased appetite
  • Fever
  • Diarrhea
  • Headache
  • Low platelet count
  • Low white blood cell count
How To Use Istodax

Istodax (Romidepsin) is administered by a healthcare professional through an intravenous infusion. It is usually given on specific days of a treatment cycle, with the exact dose and schedule determined by your doctor based on your condition and response to treatment. Regular blood tests and medical monitoring may be required to check blood cell counts, electrolyte levels, liver function, and heart rhythm during treatment.

How Istodax (Romidepsin) Works

Istodax (Romidepsin) is a histone deacetylase (HDAC) inhibitor. It blocks HDAC enzymes that help regulate proteins involved in cell growth and survival. By inhibiting these enzymes, Romidepsin causes changes in abnormal T-cells that can stop their growth and lead to their death. This helps reduce lymphoma cells and may slow the progression of T-cell lymphoma.

Storage Conditions
  • Keep the Istodax kit at controlled room temperature between 20°C and 25°C.
  • Temperature excursions between 15°C and 30°C are permitted.
  • Store both the romidepsin and supplied diluent vials together in their original carton until use.
  • Keep the product in a secure storage area away from the reach of children.
Safety Advice

AlcoholAlcohol CONSULT YOUR DOCTOR

Consult your doctor before consuming alcohol during treatment with Istodax (Romidepsin).

PregnancyPregnancy CONSULT YOUR DOCTOR

Istodax (Romidepsin) may harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant. Use effective contraception as advised by your doctor.

BreastfeedingBreastfeeding CONSULT YOUR DOCTOR

Do not breastfeed during treatment with Istodax (Romidepsin). Consult your doctor for guidance.

DrivingDriving CONSULT YOUR DOCTOR

Istodax may cause fatigue, dizziness, or weakness. Avoid driving if these symptoms affect your alertness or ability to drive safely.

KidneyKidney CAUTION

Inform your doctor if you have kidney problems before starting treatment. Your doctor may recommend appropriate monitoring.

LiverLiver CAUTION

Tell your doctor if you have liver problems. Liver function may be monitored during treatment with Istodax (Romidepsin).

Quick Tips
  • Attend all scheduled Istodax (Romidepsin) infusions and follow your doctor's treatment schedule carefully.
  • Attend regular blood tests to monitor blood cell counts, liver function, and electrolyte levels during treatment.
  • Drink adequate fluids as advised by your healthcare professional, especially if you experience vomiting or diarrhea.
  • Contact your doctor promptly if you develop fever, chills, unusual bleeding, severe weakness, dizziness, fainting, or an irregular heartbeat.
  • Inform your doctor about all medicines, vitamins, herbal products, and dietary supplements you are taking to help prevent possible drug interactions.
  • Read More About - Istodax (Romidepsin) from Pharma Five.
About Pharma Five

Pharma Five, may assist patients in arranging the import of Istodax (Romidepsin) in small quantities for personal medical use. For this purpose, the applicant is required to submit an application in Form 12A along with a prescription provided by a Registered Medical Practitioner (RMP).

With more than 20 years of pharmaceutical industry experience, Pharma Five supports patient access to Istodax (Romidepsin) and other specialized pharmaceutical products through professional import assistance. Pharma Five provides extensive pharmaceutical service coverage across India, serving patients and healthcare requirements in prominent cities such as Mumbai, Delhi, Kolkata, Bhubaneswar, Bangalore, Hyderabad, Chennai, Ahmedbad, Pune, Surat, Visakhapatnam, Jaipur, Lucknow, Nagpur, Indore, Patna, Agartala, Guwahati, Imphal, Kohima, Namchi, Noida, Ghaziabad, Ludhiana, Agra, Varanasi, Srinagar, Amritsar, Jodhpur, Chandigarh, Gurgaon, Gorakhpur, Dehradun, Jammu, Hyderabad, Thiruvananthapuram, Kochi, Coimbatore, Puducherry, Mysuru, Salem, Vellore, Tiruppur, Guntur, Goa, Kolhapur, Mumbai, Nashik, and various other regions in India.

References
  1. https://go.drugbank.com/drugs/DB06176
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/022393lbl.pdf
  3. https://www.cancer.gov/about-cancer/treatment/drugs/romidepsin
  4. https://www.ema.europa.eu/en/medicines/human/EPAR/istodax
Faq

General Question

Istodax (Romidepsin) is a prescription cancer medicine used to treat cutaneous T-cell lymphoma (CTCL) and peripheral T-cell lymphoma (PTCL) in adults who have received at least one prior treatment.

Istodax is a histone deacetylase (HDAC) inhibitor. It works by altering the expression of genes in cancer cells, stopping their growth and triggering cell death.

Istodax is prescribed for adults with CTCL or PTCL who have not responded to or have relapsed after previous treatments.

Istodax is given as an intravenous (IV) infusion, usually over a 4-hour period on days 1, 8, and 15 of a 28-day treatment cycle. It is administered in a medical setting.

Common side effects include nausea, fatigue, vomiting, loss of appetite, low blood counts, and infections.

Yes, Istodax can cause serious side effects such as heart rhythm problems (QT prolongation), severe infections, and low platelet or white blood cell counts. Contact your doctor if you experience chest pain, dizziness, or unusual bruising.

Treatment duration varies based on your response and how well you tolerate it. Your doctor will determine how many cycles are appropriate for you.

It’s best to avoid alcohol during treatment, as it may increase the risk of liver problems and worsen side effects like nausea or fatigue.

No, Istodax may harm an unborn baby. Both men and women should use effective contraception during treatment and for some time after the last dose.

Yes, Istodax can interact with other drugs, especially those affecting liver enzymes or heart rhythm. Inform your doctor of all the medications and supplements you are taking.

If you miss a scheduled IV dose, contact your healthcare provider right away. They will reschedule your infusion appropriately.

Istodax is administered via IV, so food does not affect its administration. However, eating light meals before infusions may help reduce nausea.

Attend all scheduled blood tests and check-ups, avoid contact with sick people, report any signs of infection or bleeding, and stay hydrated during treatment.

Istodax is stored and handled by medical professionals in a healthcare facility. Patients do not need to store it at home.

Istodax is available at hospitals or oncology centers where it is administered by trained healthcare professionals. Your doctor will guide you on access and scheduling. Pharma Five assists in its procurement.

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