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Buy Zaltrap (Aflibercept) Medicine in India

Zaltrap (Aflibercept)

Medicine name : Zaltrap

Generic name : Aflibercept

Manufactured By : Sanofi

Indications : mCRC

Medicine Description : Zaltrap is a VEGF inhibitor for metastatic colorectal cancer (mCRC). It blocks vascular endothelial growth factor (VEGF), inhibiting tumor blood vessel growth. Given via IV infusion, it improves survival in combination with chemotherapy. Side effects include hypertension, fatigue, diarrhea, and bleeding. Blood pressure and bleeding risk monitoring are essential.

Product Introduction

Zaltrap (Aflibercept) is a targeted anticancer treatment used in combination with other chemotherapy medicines to treat metastatic colorectal cancer in adults whose disease has progressed during or after treatment with an oxaliplatin-containing regimen. It works by blocking vascular endothelial growth factor (VEGF), which helps reduce the blood supply that tumors need to grow and spread.

Zaltrap (Aflibercept) is administered as an intravenous infusion by a qualified healthcare professional according to the treatment schedule prescribed by your doctor. It is given in combination with other chemotherapy medicines, and regular blood tests and medical check-ups are required to monitor blood pressure, blood cell counts, kidney function, and treatment response. Do not miss scheduled appointments or change your treatment without medical advice.

Common side effects of Zaltrap (Aflibercept) may include diarrhea, mouth sores, weakness, loss of appetite, weight loss, high blood pressure, headache, and abdominal pain. It may also cause serious bleeding, blood clots, gastrointestinal perforation, wound-healing problems, or kidney complications. Inform your doctor promptly if you experience unusual bleeding, severe abdominal pain, chest pain, difficulty breathing, or other serious symptoms.

Uses Of Zaltrap (Aflibercept)

Treatment of Metastatic Colorectal Cancer

Benefits Of Zaltrap

Zaltrap (Aflibercept) is used in combination with chemotherapy to treat metastatic colorectal cancer in adults whose disease has progressed during or after treatment with an oxaliplatin-containing regimen. It blocks VEGF, helping reduce the blood supply to cancer cells and slow tumor growth and disease progression.

Side Effects Of Zaltrap (Aflibercept)

Most side effects do not require medical attention and may improve as your body adjusts to the treatment. Consult your doctor if they persist, become severe, or cause concern.

Common Side Effects of Zaltrap (Aflibercept)

  • Diarrhea
  • Mouth sores
  • Weakness
  • Loss of appetite
  • Weight loss
  • High blood pressure
  • Headache
  • Abdominal pain
  • Decreased white blood cell count
  • Decreased platelet count
How To Use Zaltrap

Zaltrap (Aflibercept) is given as an intravenous infusion by a qualified healthcare professional according to the treatment schedule prescribed by your doctor. It is used in combination with other chemotherapy medicines for metastatic colorectal cancer. Regular blood tests and medical check-ups are required to monitor blood pressure, blood cell counts, kidney function, and treatment response. Do not change or stop treatment without consulting your doctor.

How Zaltrap (Aflibercept) Works

Zaltrap (Aflibercept) works by blocking vascular endothelial growth factor (VEGF), a protein that promotes the formation of new blood vessels. By reducing VEGF activity, it helps limit the blood supply that tumors need to grow and spread, thereby slowing cancer progression.

Storage Conditions
  • Store Zaltrap vials refrigerated between 2°C and 8°C.
  • Keep the vials in their original outer carton to protect them from light.
  • After dilution, the infusion solution may be refrigerated at 2°C to 8°C for up to 24 hours or kept at 20°C to 25°C for up to 8 hours.
  • Discard any unused portion remaining in the vial or infusion bag.
Safety Advice

AlcoholAlcohol CONSULT YOUR DOCTOR

Avoid or limit alcohol during treatment unless your doctor advises otherwise, as it may worsen weakness, dizziness, or other side effects.

PregnancyPregnancy CONSULT YOUR DOCTOR

Zaltrap may harm an unborn baby. Inform your doctor if you are pregnant, planning to become pregnant, or could become pregnant. Use effective contraception as advised by your doctor.

BreastfeedingBreastfeeding CONSULT YOUR DOCTOR

Do not breastfeed during treatment with Zaltrap and for the recommended period after the final dose, as advised by your healthcare professional.

DrivingDriving CONSULT YOUR DOCTOR

Zaltrap may cause dizziness, weakness, or fatigue in some people. Avoid driving or operating machinery if you feel affected.

KidneyKidney CAUTION

Inform your doctor if you have kidney problems. Your doctor may monitor kidney function, urine protein, and blood pressure during treatment.

LiverLiver CAUTION

Tell your doctor if you have liver problems. Your healthcare team may monitor liver function and your overall condition during treatment.

Quick Tips
  • Attend all scheduled Zaltrap (Aflibercept) infusions and follow your doctor's treatment schedule carefully.
  • Attend regular blood tests and medical check-ups to monitor blood pressure, blood cell counts, kidney function, and treatment response.
  • Report unusual bleeding, severe abdominal pain, chest pain, or difficulty breathing immediately.
  • Inform your doctor about all medicines, supplements, and herbal products you are taking before treatment.
  • Follow your healthcare team's instructions carefully and report any persistent or worsening side effects promptly.
  • Read More About - Zaltrap (Aflibercept) from Pharma Five.
About Pharma Five

Pharma Five, may assist patients in arranging the import of Zaltrap (Aflibercept) in small quantities for personal medical use. To facilitate the import process, the applicant must submit an application in Form 12A along with a prescription issued by a Registered Medical Practitioner (RMP).

Pharma Five provides experienced pharmaceutical consultancy services to patients requiring Zaltrap (Aflibercept), supporting access to specialized pharmaceutical products through professional import facilitation. Pharma Five provides extensive pharmaceutical service coverage across India, serving patients and healthcare requirements in prominent cities such as Mumbai, Delhi, Kolkata, Bhubaneswar, Bangalore, Hyderabad, Chennai, Ahmedbad, Pune, Surat, Visakhapatnam, Jaipur, Lucknow, Nagpur, Indore, Patna, Agartala, Guwahati, Imphal, Kohima, Namchi, Noida, Ghaziabad, Ludhiana, Agra, Varanasi, Srinagar, Amritsar, Jodhpur, Chandigarh, Gurgaon, Gorakhpur, Dehradun, Jammu, Hyderabad, Thiruvananthapuram, Kochi, Coimbatore, Puducherry, Mysuru, Salem, Vellore, Tiruppur, Guntur, Goa, Kolhapur, Mumbai, Nashik, and various other regions in India.

References
  1. https://go.drugbank.com/drugs/DB08885
  2. https://www.ema.europa.eu/fr/medicines/human/EPAR/zaltrap
  3. https://pubmed.ncbi.nlm.nih.gov/28761750/
  4. https://www.gov.uk/drug-safety-update/aflibercept-zaltrap-minimising-the-risk-of-osteonecrosis-of-the-jaw
Faq

General Question

Zaltrap (Aflibercept) is a prescription drug used to treat metastatic colorectal cancer (mCRC) in combination with chemotherapy.

Zaltrap is a vascular endothelial growth factor (VEGF) inhibitor that blocks proteins responsible for tumor growth by preventing the formation of new blood vessels.

Doctors prescribe Zaltrap for adults with metastatic colorectal cancer who have previously been treated with an oxaliplatin-based chemotherapy regimen.

Zaltrap is given as an intravenous (IV) infusion by a healthcare professional, usually once every two weeks.

Common side effects of Zaltrap include fatigue, diarrhea, high blood pressure, decreased appetite, mouth sores, and nosebleeds.

Yes, Zaltrap may cause severe bleeding, gastrointestinal perforation, compromised wound healing, and high blood pressure. Contact your doctor if serious symptoms appear.

Zaltrap is taken as part of a chemotherapy regimen, and the duration is determined by the doctor based on treatment response and tolerance.

It is best to avoid alcohol while taking Zaltrap, as it may worsen side effects like liver toxicity and increased blood pressure.

No, Zaltrap may harm an unborn baby. Women should use effective contraception while undergoing treatment.

Yes, Zaltrap may interact with other drugs, including blood thinners and certain pain relievers. Inform your doctor of all medications you are taking.

Since Zaltrap is administered in a healthcare setting, a missed dose should be rescheduled as soon as possible by your doctor.

Zaltrap is given as an IV infusion, so food intake does not affect its administration.

Avoid surgery or dental procedures during treatment, monitor blood pressure regularly, and watch for signs of bleeding or infection.

Zaltrap should be stored in a healthcare facility at controlled temperatures and prepared by professionals before administration.

Zaltrap is available by prescription and is administered in hospitals or infusion centers. Consult your doctor for treatment options. Pharma Five assists in its procurement.

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