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Buy Lazcluze (Lazertinib) Medicine in India

Lazcluze (Lazertinib)

Medicine name : Lazcluze

Generic name : Lazertinib

Manufactured By : Janssen

Indications : NSCLC-EGFR Kinase Inhibitor

Medicine Description : Lazcluze is a third-generation EGFR TKI for EGFR-mutated non-small cell lung cancer (NSCLC). It targets resistant EGFR mutations, including T790M, slowing tumor progression. Taken orally, it provides durable responses. Side effects include rash, diarrhea, liver enzyme elevation, and lung inflammation. Regular liver and lung function tests ensure safe use.

Product Introduction

Lazcluze (Lazertinib) is a targeted anticancer medicine used in combination with amivantamab to treat adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors have specific EGFR exon 19 deletions or exon 21 L858R mutations. Lazertinib is an EGFR tyrosine kinase inhibitor that blocks abnormal EGFR signaling involved in cancer cell growth and survival, helping to slow the progression of the disease.

Lazcluze (Lazertinib) should be taken exactly as prescribed by your doctor. It is usually taken once daily, with or without food, at approximately the same time each day. Swallow the tablet whole with water and do not crush, chew, or break it. Treatment is generally continued for as long as recommended by your doctor based on your response and tolerance. Regular medical check-ups and laboratory tests may be required during treatment.

Common side effects of Lazcluze may include rash, nail problems, muscle or joint pain, dry skin, diarrhea, constipation, decreased appetite, and swelling. Lazertinib may also cause serious blood clots, lung inflammation, heart problems, or eye problems. Inform your doctor promptly if you develop sudden chest pain, shortness of breath, swelling or pain in an arm or leg, new or worsening cough, vision changes, or other unusual symptoms. Before starting treatment, tell your doctor about your medical conditions and all medicines, vitamins, herbal products, and supplements you are taking.

Uses Of Lazcluze (Lazertinib)

Treatment of EGFR-Mutated Non-Small Cell Lung Cancer

Benefits Of Lazcluze

Lazcluze (Lazertinib) is used in combination with amivantamab to treat adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) with specific EGFR exon 19 deletions or exon 21 L858R mutations. It blocks abnormal EGFR signaling that promotes cancer cell growth and survival, helping to inhibit the growth of cancer cells and slow the progression of the disease. This targeted treatment may also help delay disease progression and provide better control of EGFR-mutated NSCLC.

Side Effects Of Lazcluze (Lazertinib)

Some side effects of Lazcluze (Lazertinib) may improve as your body adjusts to the medicine. Consult your doctor if any side effect persists, becomes severe, or causes concern.

Common Side Effects of Lazcluze (Lazertinib)

  • Rash
  • Nail problems
  • Muscle pain
  • Joint pain
  • Dry skin
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Swelling
  • Fatigue
How To Use Lazcluze

Lazcluze (Lazertinib) should be taken exactly as prescribed by your doctor, usually once daily, with or without food. Take it at approximately the same time each day. Swallow the tablet whole with water and do not crush, chew, or break it. Continue treatment for as long as recommended by your doctor and do not change the dose or stop treatment without medical advice.

How Lazcluze (Lazertinib) Works

Lazcluze (Lazertinib) is a targeted EGFR tyrosine kinase inhibitor. It blocks abnormal EGFR signaling caused by specific EGFR mutations, including exon 19 deletions and exon 21 L858R mutations. By inhibiting these signals, Lazertinib helps prevent cancer cells from growing and multiplying, helping to slow the progression of EGFR-mutated non-small cell lung cancer (NSCLC).

Storage Conditions
  • Keep the tablets at controlled room temperature between 20°C and 25°C.
  • Temporary temperature variations from 15°C to 30°C are permitted.
  • Store the medicine in its appropriate container and protect it from unsuitable environmental conditions.
  • Keep Lazcluze in a secure place that is out of reach of children.
Safety Advice

AlcoholAlcohol CONSULT YOUR DOCTOR

Consult your doctor before consuming alcohol during treatment with Lazcluze (Lazertinib).

PregnancyPregnancy CONSULT YOUR DOCTOR

Lazcluze (Lazertinib) may harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant. Use effective contraception as advised by your doctor.

BreastfeedingBreastfeeding CONSULT YOUR DOCTOR

Do not breastfeed during treatment with Lazcluze (Lazertinib) and for the recommended period after the final dose. Consult your doctor for guidance.

DrivingDriving CONSULT YOUR DOCTOR

Lazcluze may cause fatigue, dizziness, or vision problems. Avoid driving if these effects affect your ability to drive safely.

KidneyKidney CAUTION

Inform your doctor if you have kidney problems before starting treatment. Your doctor may recommend appropriate monitoring.

LiverLiver CAUTION

Tell your doctor if you have liver problems. Your doctor may monitor liver function during treatment.

Quick Tips
  • Take Lazcluze (Lazertinib) exactly as prescribed by your doctor and follow the recommended treatment schedule.
  • Take the tablet at approximately the same time each day and swallow it whole with water.
  • Report new or worsening cough, breathing difficulties, chest pain, or sudden shortness of breath immediately.
  • Contact your doctor if you develop swelling or pain in an arm or leg, as these may be signs of a blood clot.
  • Inform your doctor about all medicines, vitamins, herbal products, and dietary supplements you are taking to help prevent possible drug interactions.
  • Read More About - Lazcluze (Lazertinib) from Pharma Five.
About Pharma Five

Pharma Five, can facilitate the import of Lazcluze (Lazertinib) in small quantities for personal use. To initiate the process, the applicant must submit an application in Form 12A together with a prescription issued by a Registered Medical Practitioner (RMP).

Pharma Five offers professional pharmaceutical facilitation services to patients requiring Lazcluze (Lazertinib), helping them access specialized medicines through the relevant import procedures. Pharma Five provides extensive pharmaceutical service coverage across India, serving patients and healthcare requirements in prominent cities such as Mumbai, Delhi, Kolkata, Bhubaneswar, Bangalore, Hyderabad, Chennai, Ahmedbad, Pune, Surat, Visakhapatnam, Jaipur, Lucknow, Nagpur, Indore, Patna, Agartala, Guwahati, Imphal, Kohima, Namchi, Noida, Ghaziabad, Ludhiana, Agra, Varanasi, Srinagar, Amritsar, Jodhpur, Chandigarh, Gurgaon, Gorakhpur, Dehradun, Jammu, Hyderabad, Thiruvananthapuram, Kochi, Coimbatore, Puducherry, Mysuru, Salem, Vellore, Tiruppur, Guntur, Goa, Kolhapur, Mumbai, Nashik, and various other regions in India.

References
  1. https://go.drugbank.com/drugs/DB16216
  2. https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-lazertinib-amivantamab-vmjw-non-small-lung-cancer
  3. https://www.ema.europa.eu/en/medicines/human/EPAR/lazcluze
Faq

General Question

Lazcluze (Lazertinib) is a prescription medicine used to treat non-small cell lung cancer (NSCLC) in patients whose tumors have specific mutations in the EGFR gene.

Lazcluze is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It works by blocking the signals that cancer cells need to grow and divide, slowing or stopping tumor growth.

Lazcluze is prescribed for adults with EGFR mutation-positive NSCLC, especially those with the T790M resistance mutation, often after progression on earlier EGFR therapies.

Lazcluze is taken orally as a tablet once daily, with or without food, as directed by your oncologist.

Common side effects include rash, diarrhea, dry skin, itching, decreased appetite, and fatigue.

Yes, Lazcluze may cause serious side effects like interstitial lung disease, liver problems, heart rhythm changes, and eye issues. Inform your doctor if you experience shortness of breath, vision changes, or chest pain.

Lazcluze is taken continuously as long as it is effective and tolerated. Your doctor will monitor your condition and decide the duration of treatment.

It’s advisable to limit or avoid alcohol, as it may increase the risk of liver side effects and worsen fatigue or nausea.

No, Lazcluze can harm an unborn baby. Women should use effective contraception during treatment and for some time after the last dose.

Yes, Lazcluze can interact with other medications, especially those affecting liver enzymes. Let your doctor know about all the medicines and supplements you are taking.

If you miss a dose, take it as soon as you remember on the same day. If its almost time for the next dose, skip the missed dose—do not double up.

Yes, Lazcluze can be taken with or without food, but it’s best to take it at the same time each day for consistency.

Avoid excessive sun exposure, stay hydrated, monitor for lung or eye symptoms, and attend regular check-ups and blood tests.

Store Lazcluze at room temperature, away from moisture and heat, and out of reach of children.

Lazcluze is available at specialty pharmacies with a doctor’s prescription. Your oncologist or treatment center can guide you to the best source. Pharma Five assists in its procurement.

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