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Medicine name : Lazcluze
Generic name : Lazertinib
Manufactured By : Janssen
Indications : NSCLC-EGFR Kinase Inhibitor
Medicine Description : Lazcluze is a third-generation EGFR TKI for EGFR-mutated non-small cell lung cancer (NSCLC). It targets resistant EGFR mutations, including T790M, slowing tumor progression. Taken orally, it provides durable responses. Side effects include rash, diarrhea, liver enzyme elevation, and lung inflammation. Regular liver and lung function tests ensure safe use.
Lazcluze (Lazertinib) is a prescription medicine used to treat non-small cell lung cancer (NSCLC) in patients whose tumors have specific mutations in the EGFR gene.
Lazcluze is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It works by blocking the signals that cancer cells need to grow and divide, slowing or stopping tumor growth.
Lazcluze is prescribed for adults with EGFR mutation-positive NSCLC, especially those with the T790M resistance mutation, often after progression on earlier EGFR therapies.
Lazcluze is taken orally as a tablet once daily, with or without food, as directed by your oncologist.
Common side effects include rash, diarrhea, dry skin, itching, decreased appetite, and fatigue.
Yes, Lazcluze may cause serious side effects like interstitial lung disease, liver problems, heart rhythm changes, and eye issues. Inform your doctor if you experience shortness of breath, vision changes, or chest pain.
Lazcluze is taken continuously as long as it is effective and tolerated. Your doctor will monitor your condition and decide the duration of treatment.
It’s advisable to limit or avoid alcohol, as it may increase the risk of liver side effects and worsen fatigue or nausea.
No, Lazcluze can harm an unborn baby. Women should use effective contraception during treatment and for some time after the last dose.
Yes, Lazcluze can interact with other medications, especially those affecting liver enzymes. Let your doctor know about all the medicines and supplements you are taking.
If you miss a dose, take it as soon as you remember on the same day. If its almost time for the next dose, skip the missed dose—do not double up.
Yes, Lazcluze can be taken with or without food, but it’s best to take it at the same time each day for consistency.
Avoid excessive sun exposure, stay hydrated, monitor for lung or eye symptoms, and attend regular check-ups and blood tests.
Store Lazcluze at room temperature, away from moisture and heat, and out of reach of children.
Lazcluze is available at specialty pharmacies with a doctor’s prescription. Your oncologist or treatment center can guide you to the best source. Pharma Five assists in its procurement.