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Buy Lumykras (Sotorosib) Medicine in India

Lumykras (Sotorosib)

Medicine name : Lumykras

Generic name : Sotorosib

Manufactured By : Amgen

Indications : KRAS G12C mutated mNSCLC

Medicine Description : Lumykras is an KRAS G12C inhibitor for KRAS G12C-mutant non-small cell lung cancer (NSCLC). It targets the mutated KRAS protein to halt tumor growth. Taken orally, it provides a precision medicine option. Side effects include diarrhea, liver enzyme elevation, fatigue, and respiratory symptoms. Liver function and lung monitoring are required during treatment.

Product Introduction

Lumykras (Sotorasib) is a targeted anticancer treatment used for adults with KRAS G12C mutation-positive locally advanced or metastatic non-small cell lung cancer (NSCLC) whose disease has progressed after prior systemic treatment. Sotorasib specifically targets the abnormal KRAS G12C protein, helping to block signals that promote cancer cell growth and survival.

Lumykras (Sotorasib) works by binding to the altered KRAS G12C protein and locking it in an inactive state. This disrupts KRAS-driven signaling pathways that cancer cells depend on for continued growth and multiplication, helping to slow disease progression.

Lumykras (Sotorasib) should be taken exactly as prescribed by your doctor. It can generally be taken with or without food and should be swallowed whole with water. Regular medical check-ups and laboratory tests may be recommended to monitor your liver function and response to treatment. Tell your doctor about all medicines, vitamins, herbal products, or supplements you are taking before starting treatment.

Uses Of Lumykras (Sotorosib)

Treatment of KRAS G12C Mutation-Positive Non-Small Cell Lung Cancer

Benefits Of Lumykras

Lumykras (Sotorasib) is used to treat adults with KRAS G12C mutation-positive locally advanced or metastatic non-small cell lung cancer (NSCLC) whose disease has progressed after previous systemic treatment. By specifically targeting the abnormal KRAS G12C protein and blocking its cancer-promoting signals, it helps inhibit the growth and spread of cancer cells and may help slow disease progression.

Side Effects Of Lumykras (Sotorosib)

Some side effects of Lumykras (Sotorasib) may improve as the body adjusts to the treatment. Consult your doctor if any side effect persists, becomes severe, or causes concern.

Common Side Effects of Lumykras (Sotorosib)

  • Diarrhea
  • Muscle or joint pain
  • Nausea
  • Fatigue
  • Liver enzyme abnormalities
  • Cough
  • Decreased appetite
  • Vomiting
  • Constipation
  • Abdominal pain
How To Use Lumykras

Take Lumykras (Sotorasib) exactly as prescribed by your doctor, usually once daily at approximately the same time each day. It can be taken with or without food. Swallow the tablets whole with water and do not crush, chew, or break them. If you miss a dose, follow your doctor's instructions and do not take an extra dose unless advised. Continue treatment for as long as your doctor recommends.

How Lumykras (Sotorosib) Works

Lumykras (Sotorasib) is a targeted therapy that specifically blocks the KRAS G12C mutation, an abnormal protein change that can drive cancer cell growth. Sotorasib binds to the altered KRAS G12C protein and keeps it in an inactive state, disrupting signals that cancer cells use to grow and survive. This helps slow the growth and progression of KRAS G12C mutation-positive cancer.

Storage Conditions
  • Store Lumykras at a controlled room temperature of 20°C to 25°C; excursions between 15°C and 30°C are permitted.
  • Keep the tablets in their original container and protect them from unsuitable storage conditions.
  • Keep the container securely closed when not in use.
  • Store the medicine in a safe place that is out of reach of children.
Safety Advice

AlcoholAlcohol CONSULT YOUR DOCTOR

Avoid or limit alcohol unless your doctor confirms it is safe, as alcohol may increase the risk of liver-related problems during treatment.

PregnancyPregnancy CONSULT YOUR DOCTOR

Lumykras (Sotorasib) may harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant. Use effective contraception during treatment as advised by your healthcare professional.

BreastfeedingBreastfeeding CONSULT YOUR DOCTOR

It is not recommended to breastfeed during treatment with Lumykras (Sotorasib). Discuss with your doctor when breastfeeding can safely be resumed.

DrivingDriving CONSULT YOUR DOCTOR

Lumykras (Sotorasib) may cause tiredness or other symptoms that could affect alertness. Avoid driving or operating machinery if you feel unwell or unable to concentrate safely.

KidneyKidney CAUTION

Tell your doctor if you have kidney problems. Your doctor may monitor your kidney function and overall health during treatment.

LiverLiver CAUTION

Lumykras (Sotorasib) can cause liver problems and may increase liver enzymes. Tell your doctor about any existing liver condition and attend recommended liver-function tests. Report yellowing of the skin or eyes, dark urine, or unusual tiredness promptly.

Quick Tips
  • Take Lumykras (Sotorasib) exactly as prescribed and try to take it at the same time each day.
  • Drink enough fluids, especially if you experience diarrhea or vomiting, unless your doctor has advised fluid restriction.
  • Attend regular blood tests and medical appointments so your doctor can monitor liver function and treatment response.
  • Inform your doctor about all medicines, vitamins, herbal products, and supplements you are taking to avoid potential interactions.
  • Report severe or persistent diarrhea, unusual tiredness, yellowing of the skin or eyes, dark urine, or other concerning symptoms to your doctor promptly.
  • Read More About - Lumykras (Sotorosib) from Pharma Five.
About Pharma Five

Pharma Five, may assist patients with importing Lumykras (Sotorasib) in small quantities for personal medical use. For the import process, the applicant is required to submit an application in Form 12A along with a prescription issued by a Registered Medical Practitioner (RMP).

Pharma Five has over two decades of experience assisting patients with access to specialized medicines such as Lumykras (Sotorasib) through professional pharmaceutical import facilitation services. Pharma Five provides extensive pharmaceutical service coverage across India, serving patients and healthcare requirements in prominent cities such as Mumbai, Delhi, Kolkata, Bhubaneswar, Bangalore, Hyderabad, Chennai, Ahmedbad, Pune, Surat, Visakhapatnam, Jaipur, Lucknow, Nagpur, Indore, Patna, Agartala, Guwahati, Imphal, Kohima, Namchi, Noida, Ghaziabad, Ludhiana, Agra, Varanasi, Srinagar, Amritsar, Jodhpur, Chandigarh, Gurgaon, Gorakhpur, Dehradun, Jammu, Hyderabad, Thiruvananthapuram, Kochi, Coimbatore, Puducherry, Mysuru, Salem, Vellore, Tiruppur, Guntur, Goa, Kolhapur, Mumbai, Nashik, and various other regions in India.

References
  1. https://go.drugbank.com/drugs/DB15569
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/214665Orig1s009correctedlbl.pdf
  3. https://www.ema.europa.eu/fr/medicines/human/EPAR/lumykras
Faq

General Question

Lumykras (Sotorosib) is a prescription drug used to treat non-small cell lung cancer (NSCLC) with KRAS G12C mutation that has spread to other parts of the body.

Lumykras works as a KRAS G12C inhibitor, blocking the mutated KRAS protein, which is responsible for the growth and spread of cancer cells.

Doctors prescribe Lumykras for adults with advanced or metastatic KRAS G12C-mutated NSCLC who have previously received at least one prior systemic therapy.

Lumykras is taken orally in tablet form, usually once daily, with or without food.

Common side effects of Lumykras include diarrhea, fatigue, nausea, liver enzyme increases, decreased appetite, and cough.

Yes, Lumykras may cause severe liver problems, lung issues, or heart problems. Contact your doctor if you experience symptoms like yellowing of the skin or eyes, chest pain, or difficulty breathing.

Lumykras is typically taken as long as it remains effective and well-tolerated, or until your doctor advises you to stop.

It is best to avoid alcohol while taking Lumykras, as it may increase the risk of liver toxicity and other side effects.

No, Lumykras may harm an unborn baby. Women should use effective contraception while taking this medication and avoid pregnancy during treatment.

Yes, Lumykras may interact with other medications, such as certain antibiotics, antifungals, and seizure medications. Inform your doctor of all medications you are taking.

If you miss a dose, take it as soon as you remember, but skip it if the next dose is near. Do not take two doses together.

Yes, Lumykras can be taken with or without food.

Regular liver function tests are recommended, and you should avoid grapefruit. Also, limit sun exposure, and stay hydrated.

Store Lumykras at room temperature, away from moisture and heat, and keep it out of reach of children.

Lumykras is available by prescription at pharmacies or through specialty drug providers. Consult your doctor for the best source. Pharma Five assists in its procurement.

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