Top Anti Cancer Imported Medicine Drugs in India - Pharma Five

Pharma Five is a registered firm based in India. We specialize in Named Patient Imports, Imported cancer drugs, Imported medicines in india.

Contact Us Pharma Five Door No. 74, Old No. 26, Fagun Mansion, 3rd Floor, Ethiraj Salai, Egmore, Chennai - 600008 +916374297988 info@pharmafive.org
Buy Synribo (Omacetaxine) Medicine in India

Synribo (Omacetaxine)

Medicine name : Synribo

Generic name : Omacetaxine

Manufactured By : Cephalon

Indications : CML with more than 2 TKI failures

Medicine Description : Synribo is an oral chemotherapy for chronic myeloid leukemia (CML) in the chronic or accelerated phase after failure of other therapies. It inhibits protein synthesis, leading to cancer cell death. Given subcutaneously, it is effective in resistant cases. Side effects include low blood counts, injection site reactions, fatigue, and gastrointestinal symptoms. Blood tests are required to monitor for side effects.

Product Introduction

Synribo (Omacetaxine) is an anticancer treatment used for adults with chronic or accelerated phase chronic myeloid leukemia (CML) who have developed resistance or intolerance to two or more tyrosine kinase inhibitors (TKIs). Omacetaxine works through a mechanism that is different from TKIs, helping to reduce the production of proteins that cancer cells need to grow and survive.

Synribo (Omacetaxine) is a protein synthesis inhibitor that interferes with the production of certain proteins involved in leukemia cell survival. By reducing these proteins, it helps slow the growth and multiplication of abnormal blood cells and may help control the progression of CML.

Synribo (Omacetaxine) should be used exactly as prescribed by your doctor and is administered by subcutaneous injection according to the recommended treatment schedule. Regular blood tests are important to monitor blood cell counts and detect possible complications. Tell your doctor about any medical conditions and all medicines, vitamins, herbal products, or supplements you are taking before starting treatment.

Uses Of Synribo (Omacetaxine)

Treatment of Chronic Myeloid Leukemia (CML)

Benefits Of Synribo

Synribo (Omacetaxine) is used to treat adults with chronic or accelerated phase chronic myeloid leukemia (CML) whose disease has become resistant or intolerant to two or more tyrosine kinase inhibitors (TKIs). By interfering with the production of proteins that leukemia cells need for growth and survival, it helps reduce abnormal blood-cell production and may help slow the progression of CML.

Side Effects Of Synribo (Omacetaxine)

Some side effects of Synribo (Omacetaxine) may improve as the body adjusts to the treatment. Consult your doctor if any side effect persists, becomes severe, or causes concern.

Common Side Effects of Synribo (Omacetaxine)

  • Low platelet count (thrombocytopenia)
  • Low red blood cell count (anemia)
  • Low white blood cell count (neutropenia)
  • Diarrhea
  • Nausea
  • Fatigue
  • Weakness
  • Fever
  • Injection-site reactions
  • High blood sugar (hyperglycemia)
How To Use Synribo

Synribo (Omacetaxine) is given as a subcutaneous injection under the skin, usually according to a treatment schedule prescribed by your doctor. It may be administered by a healthcare professional or, after appropriate training, self-administered as instructed. Follow the prescribed schedule carefully and do not change the dose or stop treatment without medical advice. Regular blood tests are important to monitor blood-cell counts and treatment response.

How Synribo (Omacetaxine) Works

Synribo (Omacetaxine) works by inhibiting protein synthesis, which reduces the production of proteins that leukemia cells need to grow and survive. It can reduce levels of certain cancer-promoting proteins, including BCR-ABL-related proteins, helping to slow the growth and multiplication of abnormal blood cells in chronic myeloid leukemia (CML).

Storage Conditions
  • Store the unreconstituted medicine at room temperature, below 25°C.
  • Once reconstituted, keep the solution refrigerated between 2°C and 8°C and use within 12 hours.
  • Protect the medicine from direct sunlight during storage.
  • Keep the product in a safe place, out of the reach of children.
Safety Advice

AlcoholAlcohol CONSULT YOUR DOCTOR

Avoid or limit alcohol unless your doctor advises otherwise, as it may worsen fatigue, dizziness, or other treatment-related side effects.

PregnancyPregnancy CONSULT YOUR DOCTOR

Synribo (Omacetaxine) may harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant. Use effective contraception during treatment as advised by your healthcare professional.

BreastfeedingBreastfeeding CONSULT YOUR DOCTOR

Do not breastfeed during treatment with Synribo (Omacetaxine). Discuss with your doctor when it may be safe to resume breastfeeding.

DrivingDriving CONSULT YOUR DOCTOR

Synribo (Omacetaxine) may cause fatigue, weakness, dizziness, or other symptoms that can affect alertness. Avoid driving or operating machinery if you experience these effects.

KidneyKidney CAUTION

Tell your doctor if you have kidney problems before starting treatment. Your doctor may monitor your health and laboratory results during treatment.

LiverLiver CAUTION

Inform your doctor about any liver problems. Your doctor may monitor liver function and other blood-test results throughout treatment.

Quick Tips
  • Use Synribo (Omacetaxine) exactly as prescribed and follow the recommended injection schedule carefully.
  • Attend regular blood tests so your doctor can monitor blood-cell counts and detect complications early.
  • Report unusual bleeding, bruising, fever, chills, or signs of infection promptly, as treatment can lower blood-cell counts.
  • Monitor your blood sugar as advised by your doctor, especially if you have diabetes or develop symptoms of high blood sugar.
  • Inform your doctor about all medicines, vitamins, herbal products, and supplements you are taking, and report any severe or persistent side effects.
  • Read More About - Synribo (Omacetaxine) from Pharma Five.
About Pharma Five

Pharma Five, may assist patients in arranging the import of Synribo (Omacetaxine) in small quantities for personal medical use. For this purpose, the applicant must submit an application in Form 12A along with a prescription issued by a Registered Medical Practitioner (RMP). <br>

With extensive experience in the pharmaceutical industry, Pharma Five assists patients in accessing Synribo (Omacetaxine) and other specialized medicines through professional import facilitation and related services. Pharma Five provides extensive pharmaceutical service coverage across India, serving patients and healthcare requirements in prominent cities such as Mumbai, Delhi, Kolkata, Bhubaneswar, Bangalore, Hyderabad, Chennai, Ahmedbad, Pune, Surat, Visakhapatnam, Jaipur, Lucknow, Nagpur, Indore, Patna, Agartala, Guwahati, Imphal, Kohima, Namchi, Noida, Ghaziabad, Ludhiana, Agra, Varanasi, Srinagar, Amritsar, Jodhpur, Chandigarh, Gurgaon, Gorakhpur, Dehradun, Jammu, Hyderabad, Thiruvananthapuram, Kochi, Coimbatore, Puducherry, Mysuru, Salem, Vellore, Tiruppur, Guntur, Goa, Kolhapur, Mumbai, Nashik, and various other regions in India.

References
  1. https://go.drugbank.com/drugs/DB04865
  2. https://www.cancer.gov/about-cancer/treatment/drugs/omacetaxinemepesuccinate
  3. https://pubmed.ncbi.nlm.nih.gov/24309980/
Faq

General Question

Synribo (Omacetaxine mepesuccinate) is a prescription medicine used to treat adults with chronic or accelerated phase chronic myeloid leukemia (CML) who are no longer responding to or cannot tolerate two or more tyrosine kinase inhibitors (TKIs).

Synribo is a protein synthesis inhibitor. It works by preventing the cancer cells from making proteins they need to grow, leading to their death and slowing the progression of leukemia.

Synribo is intended for adults with chronic or accelerated phase CML who have failed treatment with at least two TKIs.

Synribo is administered by a healthcare provider as a subcutaneous (under the skin) injection, typically twice daily for 14 days of a 28-day cycle during the initial treatment phase.

Common side effects include low blood cell counts, diarrhea, nausea, fatigue, fever, and reactions at the injection site.

Yes, serious side effects can include severe bone marrow suppression, infections, bleeding, and low blood counts. Your doctor will monitor blood tests frequently during treatment.

Synribo treatment continues as long as it is effective and tolerable. Your doctor will assess your response and adjust your treatment plan accordingly.

It is best to avoid alcohol while taking Synribo, as it may increase the risk of liver problems and worsen side effects like fatigue or nausea.

No, Synribo can harm an unborn baby. Effective contraception should be used during treatment and for some time afterward.

Yes, Synribo may interact with other drugs. Tell your doctor about all medications, including over-the-counter medicines and supplements.

If you miss a dose, contact your healthcare provider for instructions. Do not take an extra dose without medical advice.

Synribo is given by injection and is not affected by food. However, staying well-nourished may help your body better tolerate treatment.

Avoid people who are sick, report signs of infection or bleeding, and attend all scheduled blood tests and appointments.

Synribo should be stored in the refrigerator by the healthcare facility. If you are administering it at home (under guidance), follow the storage instructions provided.

Synribo is available through specialty pharmacies or oncology centers with a valid prescription and treatment plan. Your doctor will coordinate its access and administration. Pharma Five assists in its procurement.

Timely Service
Doorstep Delivery
Hassle-Free Process
100% Genuine Sources