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Medicine name : Columvi
Generic name : Glofitamab
Manufactured By : Roche
Indications : Diffuse Large B-Cell Lymphoma or LBCL
Medicine Description : Columvi is a bispecific antibody therapy for relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It binds to CD20 on cancer cells and CD3 on T-cells, activating an immune response. Given via IV infusion, it enhances T-cell-mediated tumor destruction. Side effects include cytokine release syndrome (CRS), fever, and low blood counts. Careful monitoring helps manage severe immune reactions.
Columvi (Glofitamab) is a prescription drug used to treat certain types of non-Hodgkin’s lymphoma, particularly diffuse large B-cell lymphoma (DLBCL) in adults who have tried at least two previous treatments.
Columvi is a bispecific antibody that binds to both cancerous B-cells and immune system T-cells, helping the body’s immune system attack and destroy lymphoma cells.
Columvi is prescribed for adults with relapsed or refractory DLBCL after prior therapies have failed. A doctor will assess if it is the right treatment based on the patients condition.
Columvi is given as an intravenous (IV) infusion in a hospital or clinic setting. The dosing schedule is determined by the doctor and typically involves step-up dosing to manage side effects.
Common side effects include fever, fatigue, nausea, headache, diarrhea, low white blood cell count (neutropenia), and infusion-related reactions.
Yes, Columvi may cause serious side effects such as cytokine release syndrome (CRS), severe infections, low blood cell counts, and heart issues. Immediate medical attention is needed for severe reactions.
Treatment duration depends on the doctor’s recommendation and how well the patient responds. Columvi is usually given for a fixed number of cycles rather than long-term use.
It is best to avoid alcohol as it may worsen side effects like fatigue and liver-related complications. Consult your doctor before consuming alcohol.
No, Columvi may harm an unborn baby. Women should use effective contraception while on treatment and for some time after the last dose.
Yes, Columvi may interact with other drugs, including immunosuppressants, blood thinners, and chemotherapy agents. Inform your doctor about all the medicines you take.
If you miss an appointment for an infusion, contact your healthcare provider immediately to reschedule.
Since Columvi is given as an IV infusion, food does not directly affect it. However, maintaining proper nutrition can support overall treatment tolerance.
Monitor for infusion reactions like fever, chills, or difficulty breathing. Avoid infections by practicing good hygiene and avoiding sick individuals
Columvi is stored in a hospital or pharmacy under controlled refrigerated conditions and should only be handled by healthcare professionals.
Columvi is available by prescription and is administered in hospitals or specialty infusion centers. Consult your doctor for access and availability. Pharma Five assists in its procurement.