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Buy Tibsovo (Ivosedinib) Medicine in India

Tibsovo (Ivosedinib)

Medicine name : Tibsovo

Generic name : Ivosedinib

Manufactured By : Agios Pharmaceuticals

Indications : Relapsed or Refractory AML with a susceptible IDH mutation

Medicine Description : Tibsovo is an IDH1 inhibitor for acute myeloid leukemia (AML) with IDH1 mutations. It blocks abnormal IDH1 proteins, restoring normal cellular function. Taken orally, it improves remission rates. Side effects include differentiation syndrome, nausea, fever, and low blood counts. Blood tests and differentiation syndrome monitoring are crucial.

Product Introduction

Tibsovo (Ivosidenib) is a targeted anticancer treatment used for certain adults with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or previously treated locally advanced or metastatic cholangiocarcinoma whose cancer cells have a specific IDH1 mutation. Ivosidenib works by blocking the abnormal IDH1 protein, helping to reduce the production of substances that support cancer-cell growth and abnormal development.

Tibsovo (Ivosidenib) is an IDH1 inhibitor that targets the mutated IDH1 enzyme found in certain cancer cells. By reducing the activity of this abnormal enzyme and lowering the production of the oncometabolite 2-hydroxyglutarate, it can help restore normal cellular development and limit the growth of abnormal cancer cells.

Tibsovo (Ivosidenib) should be taken exactly as prescribed by your doctor. It may be taken with or without food, but avoid taking it with a high-fat meal because this can increase drug absorption. Regular blood tests and electrocardiograms (ECGs) may be required to monitor blood counts, electrolyte levels, heart rhythm, and treatment response. Inform your doctor about all medicines, vitamins, herbal products, or supplements you are taking before starting treatment.

Uses Of Tibsovo (Ivosedinib)

Treatment of IDH1-Mutated Cancers

Benefits Of Tibsovo

Tibsovo (Ivosidenib) is used to treat certain adults with IDH1-mutated acute myeloid leukemia (AML), relapsed or refractory myelodysplastic syndromes (MDS), and previously treated locally advanced or metastatic cholangiocarcinoma. By blocking the abnormal IDH1 protein and reducing its cancer-promoting activity, it helps restore more normal cell development, reduce the growth of abnormal cancer cells, and slow disease progression.

Side Effects Of Tibsovo (Ivosedinib)

Some side effects of Tibsovo (Ivosidenib) may improve as the body adjusts to the treatment. Consult your doctor if any side effect persists, becomes severe, or causes concern.

Common Side Effects of Tibsovo (Ivosedinib)

  • Tiredness
  • Diarrhea
  • Nausea
  • Joint pain
  • Muscle pain
  • Rash
  • Cough
  • Shortness of breath
  • Abdominal pain
  • Mouth sores
How To Use Tibsovo

Take Tibsovo (Ivosidenib) exactly as prescribed by your doctor. Swallow it whole with water and do not chew, crush, or break it. It may be taken with or without food, but avoid taking it with a high-fat meal. Follow your doctor's prescribed schedule and do not change the dose or stop treatment without medical advice.

How Tibsovo (Ivosedinib) Works

Tibsovo (Ivosidenib) works by blocking an abnormal enzyme called isocitrate dehydrogenase-1 (IDH1) that can contribute to the growth and abnormal development of certain cancer cells. By inhibiting mutated IDH1 activity, it helps reduce the production of cancer-promoting substances, supports more normal cell development, and helps slow disease progression.

Storage Conditions
  • Store Tibsovo tablets at room temperature between 20°C and 25°C; excursions between 15°C and 30°C are permitted.
  • Keep the tablets in their original bottle with the desiccant canister.
  • Do not remove the desiccant, as it helps protect the tablets from moisture.
  • Keep Tibsovo and all medicines out of the reach of children.
Safety Advice

AlcoholAlcohol CONSULT YOUR DOCTOR

Avoid or limit alcohol unless your doctor advises otherwise, as it may worsen treatment-related side effects such as tiredness, dizziness, or nausea.

PregnancyPregnancy CONSULT YOUR DOCTOR

Tibsovo (Ivosidenib) may harm an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant. Use effective contraception during treatment as advised by your healthcare professional.

BreastfeedingBreastfeeding CONSULT YOUR DOCTOR

Do not breastfeed during treatment with Tibsovo (Ivosidenib). Discuss with your doctor when breastfeeding can safely be resumed after treatment.

DrivingDriving CONSULT YOUR DOCTOR

Tibsovo (Ivosidenib) may cause tiredness, dizziness, or other symptoms that can affect alertness. Avoid driving or operating machinery if you experience these effects.

KidneyKidney CAUTION

Tell your doctor if you have kidney problems before starting treatment. Your doctor may monitor your kidney function and overall health during treatment.

LiverLiver CAUTION

Inform your doctor if you have liver problems. Regular blood tests may be recommended to monitor liver function during treatment.

Quick Tips
  • Take Tibsovo (Ivosidenib) exactly as prescribed and follow your treatment schedule consistently.
  • Avoid high-fat meals when taking Tibsovo, as they can increase the amount of medicine absorbed by the body.
  • Attend regular blood tests and ECG appointments so your doctor can monitor blood counts, electrolyte levels, heart rhythm, and treatment response.
  • Inform your doctor about all medicines, vitamins, herbal products, and supplements you are taking to help prevent interactions.
  • Report fever, shortness of breath, rapid weight gain, swelling, dizziness, fainting, or an irregular heartbeat promptly, as these may require immediate medical attention.
  • Read More About - Tibsovo (Ivosedinib) from Pharma Five.
About Pharma Five

Pharma Five, can support patients in arranging the import of Tibsovo (Ivosidenib) in small quantities for personal use. For this purpose, the applicant must submit an application in Form 12A along with a prescription provided by a Registered Medical Practitioner (RMP).

With more than 20 years of pharmaceutical industry experience, Pharma Five supports patients in accessing Tibsovo (Ivosidenib) and other specialized pharmaceutical products through professional import assistance. Pharma Five provides extensive pharmaceutical service coverage across India, serving patients and healthcare requirements in prominent cities such as Mumbai, Delhi, Kolkata, Bhubaneswar, Bangalore, Hyderabad, Chennai, Ahmedbad, Pune, Surat, Visakhapatnam, Jaipur, Lucknow, Nagpur, Indore, Patna, Agartala, Guwahati, Imphal, Kohima, Namchi, Noida, Ghaziabad, Ludhiana, Agra, Varanasi, Srinagar, Amritsar, Jodhpur, Chandigarh, Gurgaon, Gorakhpur, Dehradun, Jammu, Hyderabad, Thiruvananthapuram, Kochi, Coimbatore, Puducherry, Mysuru, Salem, Vellore, Tiruppur, Guntur, Goa, Kolhapur, Mumbai, Nashik, and various other regions in India.

References
  1. https://go.drugbank.com/drugs/DB14568
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/211192_s008lbl.pdf
  3. https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-ivosidenib-myelodysplastic-syndromes
Faq

General Question

Tibsovo (Ivosidenib) is a prescription drug used to treat acute myeloid leukemia (AML) in adults with a specific mutation in the IDH1 gene.

Tibsovo Medicine is an IDH1 inhibitor. It works by targeting and blocking the mutated IDH1 enzyme, which helps stop cancer cells from growing and multiplying.

Doctors prescribe Tibsovo for adults diagnosed with AML who have a specific IDH1 mutation. It’s used for patients who have not had prior treatment or those who are not candidates for chemotherapy.

Tibsovo Medicine is taken orally in tablet form, usually once daily, with or without food.

Common side effects of Tibsovo include fatigue, nausea, diarrhea, joint pain, fever, and decreased appetite.

Yes, Tibsovo can cause serious side effects, including differentiation syndrome (a serious complication associated with AML), liver problems, and a higher risk of infections. Seek medical attention if you experience severe symptoms.

Tibsovo is typically taken as long as it is effective and well-tolerated, or until the doctor advises stopping based on response or side effects.

It’s best to limit alcohol consumption while taking Tibsovo, as alcohol may increase the risk of liver issues and worsen some side effects.

Tibsovo is not recommended during pregnancy as it can harm an unborn baby. Women should use effective contraception during treatment.

Yes, Tibsovo may interact with other medications, including those that affect liver enzymes. Be sure to inform your doctor of all other drugs you are taking, including over-the-counter medications and supplements.

If you miss a dose, take it as soon as you remember unless it is close to the time for your next dose. Do not take two doses at once.

Yes, Tibsovo can be taken with or without food. However, taking it with food may help reduce stomach upset.

You should avoid grapefruit and grapefruit juice while on Tibsovo, as they can affect how the medicine works. Regular monitoring of liver function and blood counts is recommended during treatment.

Store Tibsovo at room temperature, away from moisture and heat, and keep it out of reach of children.

Tibsovo is available by prescription at pharmacies or through specialty pharmacies. Consult your doctor for the best option based on your location. Pharma Five assists in its procurement.

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