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Medicine name : Padcev
Generic name : Enfortumab Vedotin
Manufactured By : Astellas
Indications : Locally advanced or metastatic urothelial cancer
Medicine Description : Padcev is an antibody-drug conjugate for advanced urothelial (bladder) cancer. It binds to Nectin-4 on cancer cells, delivering a cytotoxic agent. Given via IV infusion, it improves survival. Side effects include rash, neuropathy, high blood sugar, and fatigue. Skin, nerve, and glucose monitoring are required.
Padcev (Enfortumab Vedotin) is a prescription drug used to treat advanced or metastatic urothelial cancer (bladder cancer) in adults who have previously received certain other treatments.
Padcev is an antibody-drug conjugate (ADC) that targets cancer cells by binding to a specific protein (Nectin-4) and delivering a chemotherapy-like agent to destroy them.
Doctors prescribe Padcev for adults with locally advanced or metastatic urothelial cancer who have previously been treated with a PD-1/PD-L1 inhibitor and a platinum-containing chemotherapy.
Padcev is given as an intravenous (IV) infusion by a healthcare professional, usually over a period of 30 minutes on specific treatment cycles.
Common side effects of Padcev include fatigue, nausea, decreased appetite, peripheral neuropathy, rash, dry skin, and increased blood sugar levels.
Yes, Padcev may cause serious side effects such as severe skin reactions, high blood sugar (hyperglycemia), nerve damage, or lung problems. Inform your doctor if you experience severe symptoms.
Padcev is typically taken as long as it remains effective and well-tolerated, or until the doctor recommends stopping treatment.
It is advisable to avoid alcohol while taking Padcev, as it may worsen side effects like fatigue, nausea, and liver-related issues.
No, Padcev can harm an unborn baby. Women should use effective contraception while taking this medication and for some time after the last dose.
Yes, Padcev may interact with other drugs, including certain antibiotics, antifungals, and blood thinners. Inform your doctor of all medications you are taking.
If you miss a scheduled dose of Padcev, contact your doctor or healthcare provider immediately to reschedule your infusion.
Padcev is administered intravenously and is not affected by food intake. However, maintaining a balanced diet may help manage side effects.
Avoid excessive sun exposure, stay well-hydrated, monitor blood sugar levels (if diabetic), and attend regular health check-ups while on Padcev treatment.
Padcev is stored by healthcare professionals under controlled conditions. If you need to handle it at home, follow the storage instructions provided by your doctor or pharmacist.
Padcev is available by prescription and is administered in a clinical setting. Consult your doctor or oncologist for access and availability. Pharma Five assists in its procurement.