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Medicine name : Idhifa
Generic name : Enasidenib
Manufactured By : Celgene
Indications : Relapsed or Refractory AML
Medicine Description : Idhifa is an IDH2 inhibitor for relapsed or refractory acute myeloid leukemia (AML) with IDH2 mutations. It blocks abnormal IDH2 proteins, reducing cancer cell growth. Taken orally, it offers a targeted approach. Side effects include differentiation syndrome, nausea, jaundice, and low blood counts. Patients require regular monitoring for differentiation syndrome, which can be life-threatening if untreated.
Idhifa (Enasidenib) is a prescription medication used to treat acute myeloid leukemia (AML) in adults with an IDH2 mutation who have relapsed or are resistant to previous treatment.
Idhifa works as an IDH2 inhibitor, blocking the mutated IDH2 enzyme to help restore normal blood cell production and slow cancer growth.
Idhifa is prescribed for adults with relapsed or refractory AML that has an IDH2 gene mutation, as confirmed by a doctor through genetic testing.
Idhifa is taken orally in tablet form, usually once daily, with or without food.
Common side effects of Idhifa include nausea, vomiting, diarrhea, decreased appetite, jaundice, and increased bilirubin levels.
Yes, Idhifa may cause differentiation syndrome, severe liver toxicity, and high blood bilirubin levels. Contact your doctor if severe symptoms appear.
Idhifa is typically taken as long as it remains effective and well-tolerated, or until the doctor advises stopping.
It is best to avoid alcohol while taking Idhifa, as it may worsen liver-related side effects.
No, Idhifa may harm an unborn baby. Women should use effective contraception while taking this medication.
Yes, Idhifa may interact with certain antibiotics, antifungals, and seizure medications. Inform your doctor of all medicines you take.
If you miss a dose, take it as soon as you remember. However, if it’s close to your next dose, skip the missed one. Do not take two doses at once.
Yes, Idhifa can be taken with or without food, but taking it with food may help reduce nausea.
Regular blood tests are necessary to monitor liver function and bilirubin levels. Avoid grapefruit and stay hydrated.
Store Idhifa at room temperature, away from moisture and heat, and keep it out of reach of children.
Idhifa is available by prescription at specialty pharmacies. Consult your doctor for the best source. Pharma Five assists in its procurement.