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Medicine name : Danyelza
Generic name : Naxitamab
Manufactured By : Mabs Therapeutics
Indications : Neuroblastoma
Medicine Description : A monoclonal antibody therapy used to treat relapsed or refractory high-risk neuroblastoma in pediatric patients. It targets GD2, a protein on neuroblastoma cells, enhancing the immune system’s ability to attack and destroy cancerous cells.
Danyelza (Naxitamab) is a prescription medicine used to treat children aged 1 year and older, and adults, with high-risk neuroblastoma in the bone or bone marrow that has either returned or did not respond to earlier treatment.
Danyelza is a monoclonal antibody that targets the GD2 protein on the surface of neuroblastoma cells. It helps the immune system find and destroy these cancer cells.
Danyelza is approved for use in patients aged 1 year and older with relapsed or refractory high-risk neuroblastoma affecting the bone or bone marrow, and who have shown at least a partial response to previous therapy.
Danyelza is given as an intravenous (IV) infusion, typically three times a week for two consecutive weeks of a 4-week cycle. It’s administered in combination with GM-CSF (a growth factor), under close medical supervision.
Common side effects include infusion-related reactions (like fever, chills, or low blood pressure), pain, vomiting, decreased appetite, fatigue, and cough.
Yes, serious side effects can include severe infusion reactions, high blood pressure, allergic reactions, nerve pain, and bone marrow suppression. These are closely monitored during treatment.
Treatment continues in cycles as long as the patient benefits and tolerates the therapy well. The healthcare provider will decide the duration based on individual response and side effects.
It is best to avoid alcohol during treatment, as it may worsen side effects like liver stress or fatigue and interfere with recovery.
No, Danyelza may harm an unborn baby. Effective birth control should be used during treatment and for a period afterward. Patients should not breastfeed during treatment.
Yes, Danyelza may interact with other medications or increase the risk of side effects. Inform your doctor of all medicines, supplements, or treatments you are taking.
If a dose is missed, contact your healthcare provider immediately. Doses should only be administered in a clinical setting by medical professionals.
Danyelza is not taken by mouth, so food does not directly impact its administration. However, patients should maintain good nutrition during treatment for better recovery.
Attend all scheduled appointments, watch for signs of infusion reactions, maintain good hygiene to avoid infections, and follow your doctor’s advice on managing pain or side effects.
Danyelza is stored and prepared by medical professionals in a healthcare setting. It is not stored at home.
Danyelza is administered at specialized cancer centers or hospitals by trained medical staff with a valid prescription and treatment plan. Pharma Five assists in its procurement.