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Medicine name : Besponsa
Generic name : Inotuzumab Ozogamicin
Manufactured By : Pfizer
Indications : Relapsed or Refractory B-Cell precursor ALL
Medicine Description : Besponsa is an antibody-drug conjugate used for relapsed or refractory B-cell acute lymphoblastic leukemia (ALL). It targets CD22 on cancer cells, delivering a cytotoxic agent to induce cell death. Administered via IV infusion, it improves remission rates. Side effects include liver toxicity, low blood counts, and infusion reactions. Patients are closely monitored for veno-occlusive disease (VOD) and liver function.
Besponsa (Inotuzumab Ozogamicin) is a prescription cancer medication used to treat adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (B-ALL).
Besponsa is an antibody-drug conjugate. It targets the CD22 protein on cancer cells and delivers a toxin directly to those cells, helping to kill them while sparing most healthy cells.
Besponsa is prescribed to adults with B-cell ALL who have not responded to or have relapsed after previous treatments.
Besponsa is given by intravenous (IV) infusion in cycles, usually once a week for 3 weeks in a 21- to 28-day cycle, under the supervision of a healthcare professional.
Common side effects include fatigue, nausea, headache, fever, low blood cell counts, and increased risk of infections.
Yes, Besponsa may cause serious side effects such as liver damage (including veno-occlusive disease), low blood counts, infections, and infusion-related reactions. Inform your doctor if you notice yellowing of the skin, swelling, or breathing difficulties.
The treatment duration depends on how you respond and how well you tolerate the medicine. Your doctor will determine the number of cycles needed.
It is best to avoid alcohol while on Besponsa, as it may increase the risk of liver damage and intensify side effects.
No, Besponsa may harm an unborn baby. Women should use effective contraception during treatment and for some time after the last dose.
Yes, Besponsa can interact with other drugs. Inform your doctor about all medications, including over-the-counter drugs and supplements.
Besponsa is administered in a clinical setting, so your healthcare provider will manage missed doses or rescheduling.
Besponsa is given via IV, so it is not affected by food intake.
Have regular blood tests to monitor liver function and blood counts, avoid infection exposure, and report any unusual symptoms like abdominal pain, weight gain, or jaundice.
Besponsa is stored and handled by healthcare professionals in hospitals or infusion centers.
Besponsa is available by prescription and is administered in specialized medical facilities. Speak with your oncologist for access and treatment planning. Pharma Five assists in its procurement.