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Medicine name : Inrebic
Generic name : Fedratinib
Manufactured By : Celgene
Indications : Myelofibrosis
Medicine Description : Inrebic is a JAK2 inhibitor used for myelofibrosis, a bone marrow cancer. It reduces spleen size and alleviates symptoms like anemia and fatigue. Taken orally, it improves quality of life. Side effects include nausea, diarrhea, dizziness, and severe brain complications (Wernicke’s encephalopathy). Patients need thiamine level monitoring to prevent neurological risks.
Inrebic (Fedratinib) is a prescription medication used to treat myelofibrosis, a type of bone marrow cancer that disrupts normal blood cell production.
Inrebic is a Janus kinase 2 (JAK2) inhibitor that helps reduce symptoms of myelofibrosis by blocking the abnormal signals that cause bone marrow scarring and enlarged spleen.
Doctors prescribe Inrebic for adults with intermediate-2 or high-risk primary or secondary myelofibrosis.
Inrebic is taken orally as a capsule, usually once daily, with or without food.
Common side effects include nausea, diarrhea, vomiting, dizziness, fatigue, and low blood cell counts.
Yes, Inrebic may cause serious side effects such as severe anemia, neurological problems (including Wernicke’s encephalopathy), and liver toxicity. Seek medical help for severe symptoms.
Inrebic is taken as long as it remains effective and tolerable, or until a doctor advises stopping treatment.
It is best to avoid alcohol while taking Inrebic, as it may increase the risk of liver problems and worsen side effects.
No, Inrebic may harm an unborn baby. Women should use effective contraception while taking this medication.
Yes, Inrebic can interact with certain medications, including antifungals, antibiotics, and seizure drugs. Inform your doctor about all medications you take.
If you miss a dose, take it as soon as you remember, but skip it if your next dose is soon. Do not take two doses together.
Yes, Inrebic can be taken with or without food, but taking it with a meal may help reduce stomach discomfort.
Drink plenty of fluids to prevent dehydration, monitor blood counts regularly, and avoid grapefruit while taking Inrebic.
Store Inrebic at room temperature, away from moisture and heat, and keep it out of reach of children.
Inrebic is available by prescription at pharmacies or through specialty drug providers. Consult your doctor for the best source. Pharma Five assists in its procurement.