Top Anti Cancer Imported Medicine Drugs in India - Pharma Five

Pharma Five is a registered firm based in India. We specialize in Named Patient Imports, Imported cancer drugs, Imported medicines in india.

Contact Us Pharma Five Door No. 74, Old No. 26, Fagun Mansion, 3rd Floor, Ethiraj Salai, Egmore, Chennai - 600008 +916374297988 info@pharmafive.org
Buy Pemazyre (Pemagatinib) Medicine in India

Pemazyre (Pemagatinib)

Medicine name : Pemazyre

Generic name : Pemagatinib

Manufactured By : Incyte Biosciences

Indications : Locally advanced or metastatic cholangiocarcinoma

Medicine Description : Pemazyre is an FGFR inhibitor for cholangiocarcinoma (bile duct cancer) with FGFR2 fusions. It blocks FGFR signaling, slowing tumor growth. Taken orally, it provides a targeted approach. Side effects include high phosphate levels, eye disorders, fatigue, and gastrointestinal issues. Electrolyte and eye monitoring are required.

Product Introduction

Pemazyre (Pemigatinib) is a targeted anticancer medicine used to treat certain adults with advanced or metastatic cholangiocarcinoma (bile duct cancer) whose tumors have a specific FGFR2 fusion or rearrangement and have progressed after at least one prior systemic treatment. It may also be used to treat certain adults with myeloid or lymphoid neoplasms with an FGFR1 rearrangement. Pemigatinib works by blocking abnormal FGFR signaling involved in cancer cell growth and survival, helping to slow the progression of the disease.

Pemazyre (Pemigatinib) should be taken exactly as prescribed by your doctor. It is usually taken once daily according to a specific treatment schedule and may be taken with or without food. Swallow the tablet whole with water and do not crush, chew, or break it. Regular eye examinations and blood tests may be required during treatment to monitor your eyes, phosphate levels, liver function, kidney function, and overall response to therapy.

Common side effects of Pemazyre may include high phosphate levels, hair loss, diarrhea, dry mouth, fatigue, changes in taste, nausea, constipation, dry skin, and mouth sores. Pemigatinib may also cause serious eye problems and changes in phosphate levels. Inform your doctor promptly if you experience blurred or changed vision, eye pain, severe weakness, muscle cramps, confusion, or other unusual symptoms. Before starting treatment, tell your doctor about all medical conditions and medicines, vitamins, herbal products, and supplements you are taking.

Uses Of Pemazyre (Pemagatinib)

Treatment of FGFR2-Altered Bile Duct Cancer

Benefits Of Pemazyre

Pemazyre (Pemigatinib) is used to treat certain adults with advanced or metastatic cholangiocarcinoma (bile duct cancer) whose tumors have an FGFR2 fusion or rearrangement and have progressed after previous systemic treatment. It works by blocking abnormal FGFR signaling, which helps control cancer cell growth and survival, thereby helping to slow tumor growth and disease progression. Pemigatinib may also be used for certain FGFR1-rearranged myeloid or lymphoid neoplasms, helping control the abnormal growth of affected blood cells.

Side Effects Of Pemazyre (Pemagatinib)

Some side effects of Pemazyre (Pemigatinib) may improve as the body adjusts to the medicine. Consult your doctor if any side effect persists, becomes severe, or causes concern.

Common Side Effects of Pemazyre (Pemagatinib)

  • High phosphate levels in the blood (hyperphosphatemia)
  • Hair loss
  • Diarrhea
  • Dry skin
  • Nausea
  • Constipation
  • Mouth sores (stomatitis)
  • Decreased appetite
  • Nail changes
  • low phosphate levels
How To Use Pemazyre

Take Pemazyre (Pemigatinib) exactly as prescribed by your doctor. It is usually taken once daily according to the recommended treatment schedule and may be taken with or without food. Swallow the tablet whole with water and do not crush, chew, or break it. Take it at approximately the same time each day. If you miss a dose, follow your doctor's instructions rather than taking an extra dose to make up for it. Continue treatment for as long as recommended by your healthcare professional.

How Pemazyre (Pemagatinib) Works

Pemazyre contains Pemigatinib, a targeted medicine that blocks fibroblast growth factor receptors (FGFRs), particularly FGFR1, FGFR2, and FGFR3. These receptors can send signals that promote abnormal cancer cell growth and survival. By inhibiting FGFR signaling, Pemigatinib helps slow the growth and spread of cancer cells in tumors with specific FGFR abnormalities.

Storage Conditions
  • Maintain the medicine at a controlled room temperature of 20°C to 25°C.
  • Keep it in a dry area away from excessive heat and humidity.
  • Leave the product in its original packaging until it is needed.
  • Store the medicine securely where children cannot reach it.
Safety Advice

AlcoholAlcohol CONSULT YOUR DOCTOR

Consult your doctor before consuming alcohol during treatment with Pemazyre (Pemigatinib).

PregnancyPregnancy CONSULT YOUR DOCTOR

Pemazyre may cause serious harm to an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant. Use effective contraception during treatment as advised by your doctor.

BreastfeedingBreastfeeding CONSULT YOUR DOCTOR

Breastfeeding is not recommended during treatment with Pemazyre. Consult your doctor for guidance on when breastfeeding can be safely resumed.

DrivingDriving CONSULT YOUR DOCTOR

Pemazyre may cause fatigue, dizziness, or vision changes that can affect your ability to drive safely. Avoid driving if your vision or alertness is affected.

KidneyKidney CAUTION

Inform your doctor if you have kidney problems before starting treatment. Dose adjustments or additional monitoring may be required.

LiverLiver CAUTION

Tell your doctor if you have liver problems. Pemazyre may require additional monitoring or dose adjustment in patients with liver impairment.

Quick Tips
  • Take Pemazyre exactly as prescribed by your doctor and follow the recommended treatment schedule.
  • Swallow the tablet whole with water. Do not crush, chew, or break it.
  • Take your doses at approximately the same time each day, with or without food.
  • Attend regular blood tests and eye examinations as recommended by your doctor.
  • Inform your doctor promptly about vision changes, severe weakness, muscle cramps, or any unusual or worsening side effects.
  • Read More About - Pemazyre (Pemagatinib) from Pharma Five.
About Pharma Five

Pharma Five, can assist patients in arranging the import of Pemazyre (Pemigatinib) in small quantities for personal use. For this purpose, the applicant is required to submit an application in Form 12A along with a prescription provided by a Registered Medical Practitioner (RMP).

Pharma Five assists patients requiring Pemazyre (Pemigatinib) through professional pharmaceutical facilitation services, helping them access this and other specialized medicines through the relevant import process. Pharma Five provides extensive pharmaceutical service coverage across India, serving patients and healthcare requirements in prominent cities such as Mumbai, Delhi, Kolkata, Bhubaneswar, Bangalore, Hyderabad, Chennai, Ahmedbad, Pune, Surat, Visakhapatnam, Jaipur, Lucknow, Nagpur, Indore, Patna, Agartala, Guwahati, Imphal, Kohima, Namchi, Noida, Ghaziabad, Ludhiana, Agra, Varanasi, Srinagar, Amritsar, Jodhpur, Chandigarh, Gurgaon, Gorakhpur, Dehradun, Jammu, Hyderabad, Thiruvananthapuram, Kochi, Coimbatore, Puducherry, Mysuru, Salem, Vellore, Tiruppur, Guntur, Goa, Kolhapur, Mumbai, Nashik, and various other regions in India.

References
  1. https://go.drugbank.com/drugs/DB15102
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/213736s000lbl.pdf
  3. https://www.ema.europa.eu/en/medicines/human/EPAR/pemazyre
  4. https://www.cancer.gov/publications/dictionaries/cancer-drug/def/pemigatinib
Faq

General Question

Pemazyre (Pemigatinib) is a prescription drug used to treat bile duct cancer (cholangiocarcinoma) that has a specific genetic mutation (FGFR2 fusion or rearrangement).

Pemazyre is a kinase inhibitor that blocks FGFR (fibroblast growth factor receptor) proteins, which helps slow down or stop the growth of cancer cells.

Doctors prescribe Pemazyre for adults with advanced or metastatic cholangiocarcinoma who have FGFR2 fusion or rearrangement and have already undergone previous treatments.

Pemazyre is taken orally in tablet form once daily for 14 days, followed by a 7-day break, in a 21-day treatment cycle.

Common side effects of Pemazyre include dry eyes, mouth sores, nausea, fatigue, diarrhea, dry skin, and taste changes.

Yes, Pemazyre may cause serious side effects, including high phosphate levels, eye disorders, kidney problems, and severe infections. Consult your doctor if severe symptoms appear.

Pemazyre is typically taken as long as it remains effective and well-tolerated, or until your doctor recommends stopping.

It is best to avoid alcohol while taking Pemazyre, as it may worsen side effects like dehydration, fatigue, and liver issues.

No, Pemazyre may harm an unborn baby. Women should use effective contraception while taking this medication.

Yes, Pemazyre may interact with other drugs, including certain antibiotics, antifungals, and seizure medications. Inform your doctor of all medicines you take.

If you miss a dose of Pemazyre, take it as soon as you remember, but skip it if your next dose is soon. Do not take two doses together.

Yes, Pemazyre can be taken with or without food.

Avoid grapefruit, protect your eyes from excessive light, and ensure regular health check-ups while taking Pemazyre.

Store Pemazyre at room temperature, away from moisture and heat, and keep it out of reach of children.

Pemazyre is available by prescription at pharmacies or through specialty drug providers. Consult your doctor for the best source. Pharma Five assists in its procurement.

Timely Service
Doorstep Delivery
Hassle-Free Process
100% Genuine Sources