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Medicine name : Pemazyre
Generic name : Pemagatinib
Manufactured By : Incyte Biosciences
Indications : Locally advanced or metastatic cholangiocarcinoma
Medicine Description : Pemazyre is an FGFR inhibitor for cholangiocarcinoma (bile duct cancer) with FGFR2 fusions. It blocks FGFR signaling, slowing tumor growth. Taken orally, it provides a targeted approach. Side effects include high phosphate levels, eye disorders, fatigue, and gastrointestinal issues. Electrolyte and eye monitoring are required.
Pemazyre (Pemigatinib) is a prescription drug used to treat bile duct cancer (cholangiocarcinoma) that has a specific genetic mutation (FGFR2 fusion or rearrangement).
Pemazyre is a kinase inhibitor that blocks FGFR (fibroblast growth factor receptor) proteins, which helps slow down or stop the growth of cancer cells.
Doctors prescribe Pemazyre for adults with advanced or metastatic cholangiocarcinoma who have FGFR2 fusion or rearrangement and have already undergone previous treatments.
Pemazyre is taken orally in tablet form once daily for 14 days, followed by a 7-day break, in a 21-day treatment cycle.
Common side effects of Pemazyre include dry eyes, mouth sores, nausea, fatigue, diarrhea, dry skin, and taste changes.
Yes, Pemazyre may cause serious side effects, including high phosphate levels, eye disorders, kidney problems, and severe infections. Consult your doctor if severe symptoms appear.
Pemazyre is typically taken as long as it remains effective and well-tolerated, or until your doctor recommends stopping.
It is best to avoid alcohol while taking Pemazyre, as it may worsen side effects like dehydration, fatigue, and liver issues.
No, Pemazyre may harm an unborn baby. Women should use effective contraception while taking this medication.
Yes, Pemazyre may interact with other drugs, including certain antibiotics, antifungals, and seizure medications. Inform your doctor of all medicines you take.
If you miss a dose of Pemazyre, take it as soon as you remember, but skip it if your next dose is soon. Do not take two doses together.
Yes, Pemazyre can be taken with or without food.
Avoid grapefruit, protect your eyes from excessive light, and ensure regular health check-ups while taking Pemazyre.
Store Pemazyre at room temperature, away from moisture and heat, and keep it out of reach of children.
Pemazyre is available by prescription at pharmacies or through specialty drug providers. Consult your doctor for the best source. Pharma Five assists in its procurement.