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Imlunestrant (Inluriyo)

Medicine name : Imlunestrant

Generic name : Inluriyo

Manufactured By : Eli Lilly

Indications : ER+ HER2- ve ESR1-advanced breast cancer

Medicine Description : A targeted oral therapy for ER-positive, HER2-negative advanced breast cancer, Imlunestrant (Inluriyo) is a next-generation selective estrogen receptor degrader (SERD) that blocks and degrades estrogen receptors, including tumors with ESR1 mutations, to slow cancer progression. It is used in patients whose disease has progressed after prior endocrine therapy. Taken orally, it helps improve progression-free survival. Common side effects include nausea, fatigue, hot flashes, and joint pain. Regular monitoring is recommended to manage treatment-related adverse effects and overall tolerability.

Product Introduction

Imlunestrant (Inluriyo) is a targeted anticancer treatment used to treat adults with estrogen receptor-positive (ER-positive), HER2-negative, ESR1-mutated advanced or metastatic breast cancer whose disease has progressed following at least one line of endocrine therapy. It belongs to a group of medicines called estrogen receptor antagonists and works by blocking estrogen receptor signaling that can promote the growth and survival of certain breast cancer cells, helping to slow disease progression.

Imlunestrant (Inluriyo) should be taken exactly as prescribed by your doctor. It is taken orally once daily on an empty stomach, at least 2 hours before food or 1 hour after food. Swallow it whole with water and do not crush, chew, or break it. Regular medical check-ups and laboratory tests may be required to monitor your response to treatment and overall health.

Common side effects of Imlunestrant (Inluriyo) may include musculoskeletal pain, fatigue, diarrhea, nausea, constipation, abdominal pain, decreased blood cell counts, and changes in liver function tests. Inform your doctor if any side effect becomes severe or persistent. Before starting treatment, tell your doctor about your medical history and all medicines, vitamins, and supplements you are taking.

Uses Of Imlunestrant (Inluriyo)

Treatment of ESR1-Mutated Breast Cancer

Benefits Of Imlunestrant

Imlunestrant (Inluriyo) is used to treat adults with estrogen receptor-positive (ER-positive), HER2-negative, ESR1-mutated advanced or metastatic breast cancer after progression on at least one line of endocrine therapy. It blocks estrogen receptor signaling, helping to slow the growth and progression of cancer cells.

Side Effects Of Imlunestrant (Inluriyo)

Some side effects of Imlunestrant (Inluriyo) may improve as the body adjusts to the treatment. Consult your doctor if any side effect persists, becomes severe, or causes concern.

Common Side Effects of Imlunestrant (Inluriyo)

  • Musculoskeletal pain
  • Fatigue
  • Diarrhea
  • Hot flashes
  • Decreased appetite
  • Nausea
  • Constipation
  • Headache
  • Increased cholesterol levels
  • Decreased hemoglobin levels
How To Use Imlunestrant

Take Imlunestrant (Inluriyo) exactly as prescribed by your doctor, usually once daily on an empty stomach. Take it at approximately the same time each day, at least 2 hours before food or 1 hour after food. Swallow it whole with water and do not crush, chew, or break it. Follow your doctor's instructions if you miss a dose or vomit after taking it.

How Imlunestrant (Inluriyo) Works

Imlunestrant (Inluriyo) is an estrogen receptor antagonist that binds to and blocks estrogen receptors in cancer cells. It also promotes the breakdown of estrogen receptors, reducing estrogen-driven signals that can help certain breast cancer cells grow and survive. This helps slow cancer growth and disease progression.

Safety Advice

AlcoholCONSULT YOUR DOCTOR

Limit or avoid alcohol during treatment, as it may worsen side effects such as fatigue, nausea, or dizziness. Follow your doctor's advice.

PregnancyCONSULT YOUR DOCTOR

Inluriyo may harm an unborn baby. Women who can become pregnant should use effective contraception during treatment and for the recommended period after the last dose.

BreastfeedingCONSULT YOUR DOCTOR

Do not breastfeed during treatment and for the recommended period after the last dose, as the effects on a breastfed child are not fully known.

DrivingCONSULT YOUR DOCTOR

Avoid driving or operating machinery if you experience fatigue, dizziness, or other effects that may impair your alertness.

KidneyCAUTION

Inform your doctor if you have kidney problems. Your doctor may monitor kidney function and provide appropriate medical care during treatment.

LiverCAUTION

Tell your doctor about any liver condition. Regular liver function tests may be recommended, and report yellowing of the skin or eyes, dark urine, or unusual tiredness promptly.

Quick Tips
  • Take Imlunestrant (Inluriyo) exactly as prescribed and follow the recommended daily schedule.
  • Take it on an empty stomach and follow the recommended timing around meals consistently.
  • Report persistent diarrhea, nausea, fatigue, or musculoskeletal pain if these symptoms become severe or troublesome.
  • Attend regular medical check-ups and laboratory tests to monitor your response to treatment and overall health.
  • Tell your doctor about all medicines, vitamins, and supplements you are taking before and during treatment.
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